What Is Sofa Criteria For Sepsis

By Sofia | August 1, 2018

What Is SOFA Criteria for Sepsis?

The Sequential Organ Failure Assessment (SOFA) score is a tool used to assess the severity of organ dysfunction in patients with sepsis. It is a widely accepted and validated scoring system that helps clinicians determine the severity of sepsis and guide treatment decisions.

Components of the SOFA Score

The SOFA score is calculated based on six physiological parameters:

  • Respiratory system: PaO2/FiO2 ratio
  • Coagulation system: Platelet count
  • Hepatic system: Bilirubin level
  • Cardiovascular system: Mean arterial pressure
  • Central nervous system: Glasgow Coma Scale
  • Renal system: Creatinine level

Scoring System

Each parameter is assigned a score from 0 to 4, depending on its severity:

Parameter Score
PaO2/FiO2 ratio 0-4
Platelet count 0-4
Bilirubin level 0-4
Mean arterial pressure 0-4
Glasgow Coma Scale 0-4
Creatinine level 0-4

The total SOFA score is the sum of the scores for all six parameters, ranging from 0 to 24.

Interpretation of the SOFA Score

The SOFA score helps categorize sepsis severity as follows:

SOFA Score Sepsis Severity
0-4 No organ failure
5-8 Mild organ failure
9-12 Moderate organ failure
13-16 Severe organ failure
≥17 Critical organ failure

A higher SOFA score indicates more severe organ dysfunction and a higher risk of mortality.

Limitations of the SOFA Score

While the SOFA score is a useful tool for assessing sepsis severity, it has some limitations:

  • It does not account for all organ systems.
  • It may not be sensitive enough to detect early sepsis.
  • It is affected by pre-existing organ dysfunction.
  • Conclusion

    The SOFA score is a valuable tool for assessing organ dysfunction in patients with sepsis. It helps clinicians determine the severity of the condition and guides treatment decisions. However, it should be used in conjunction with other clinical information and assessments to ensure accurate diagnosis and management.


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